Relectura: The computational limit of genetic reductionism and materialist illusion

Researchers publish in Nature a comprehensive model of the cellular transcriptome, revealing that the computational power required to predict protein folding and cellular differentiation from linear DNA sequence alone exceeds the physical limits of the observable universe. The study concludes that there must be a layer of pre-existing 'structural epigenetic information' that acts as computational scaffolding, challenging the paradigm of absolute genetic determinism.